Prior to taking evening primrose oil, consider precautions and warnings such as potential side effects, contraindications, and interactions with different herbs, and with supplements and medications. Some general points are mentioned on this page, however, these are not meant to be professional or qualified medical advice, nor is this page intended to be a complete list of such precautions.

Side effects

Generally reported side effects of taking evening primrose oil are mild and uncommon. They may include headache, nausea, and stomach pain. When taken at the recommended dosage levels, EPO is considered generally safe. If doses are too high, loose stools and stomach pain may come as symptoms.

Evening primrose oil is considered to be safe to take while breastfeeding. Breast milk already contains gamma-linolenic acid (GLA) and linoleic acid (LA). Please get professional medical assistance, however, and consider other possible items, such as the condition of the baby or infant.

Contraindications

Evening primrose oil may have contraindications in particular patients. For one such example, those who have a blood disorder or bleeding problem should not take EPO. Another such instance is with individuals who have a seizure disorder, in which case any omega-6 supplements (for instance evening primrose oil and gamma-linolenic acid, amongst others) should not be taken. Consider other conditions that you may have prior to taking this herbal medicine.

Interactions

Are you taking any medications (prescription or over-the-counter)? Evening primrose oil may change the effects of these in some cases. In particular, although not an exhaustive list, the following medications may have interactions with EPO: phenothiazines, nonsteroidal anti-inflammatory drugs (NSAIDs), and antiplatelet and anticoagulant medications.

Additionally, consider any possible interactions with other herbs, as well as supplements. For instance, one possible interaction is with other herbs that act as blood thinners.